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Guardian™ 4 Smart Continuous Glucose Monitoring System with InPen™ Smart Insulin Pen System

Stay ahead of your glucose levels with our first Smart MDI* system1,2

Guardian™ 4 Smart Continuous Glucose Monitoring System with InPen™ Smart Insulin Pen System

What is a  Smart MDI System?

The Smart MDI system combines the power of our latest innovation in continuous glucose monitoring (CGM), Guardian™ 4 Smart* CGM system with the InPen™ Smart** Insulin Pen System.***

The InPen™ system is designed to assist with tracking of insulin doses and dose calculations

Guardian™ 4 CGM system tracks your glucose levels 24/7 every 5 minutes, whilst the InPen™ system helps you take the right insulin dose at the right time.

Combining the power of real time glucose readings with predictive alerts and personalised insulin dosing* to help you stay ahead of your glucose levels1,2. The Smart MDI system can help to improve your Time in Range**(TIR).

Know before you go low or high with real-time blood glucose readings, trends and alerts.

1

Help prevent highs, alerting if you are trending high.

2

Help prevent lows, alerting if you are at low, or trending low.

17:0012:00Meal6.5 mmol/L 125.2 mmol/L
Glucose levels mmol/L
Predictive alerts
Bolus calculator
Bolus insulin
Active insulin
12:0017:00Meal6.5 mmol/L5.2 mmol/L1212
Glucose levels mmol/L
Predictive alerts
Bolus calculator
Bolus insulin
Active insulin

All this information available in the InPen™ app

*/
Sarah

It is so helpful to be able to see all my trends and not have to be checking my blood sugar every 5 minutes.

- Sarah, Smart MDI system user

Frequently asked questions

The Smart MDI System brings together an ecosystem of smart tools that provide real-time insights and comprehensive reports to make it easier to manage life on MDI.

  • The Guardian 4 system is a real-time, Continuous Glucose Monitoring (CGM) system indicated for the management of diabetes in persons aged 7 years and older.
  • The InPen system is intended for single-patient use by people with diabetes for the self-injection of a desired dose of insulin. For patients who do not self-manage their diabetes, the use of InPen™ should always be under the supervision of a caregiver.

We’ve updated our standalone CGM system app and hardware to improve the customer experience. These are the most significant updates that can be found in the Guardian™ 4 system:

  • The previous system was called the Guardian™ Connect system. This next generation of our Smart CGM is called the Guardian™ 4 Smart* CGM System
  • The Guardian™ 4 system now requires no finger pricks**
  • Non-adjunctive labeling. This means a user can now make treatment decisions based on the glucose value shown by the system, without the need for a confirmatory finger prick.

 

*Smart CGM predicts future high and low sensor glucose events up to 1 hour in advance and provides access to additional algorithms and insights that can inform users of clinically relevant glucose patterns. Please refer to IFU.

**If CGM readings do not match symptoms or expectations, use a blood glucose meter to make diabetes treatment decisions. Refer to System User Guide.

At this time, InPen™ system is compatible with Lilly Humalog®, Lilly Lyumjev®, Novo Nordisk NovoRapid®, Novo Nordisk Fiasp® and Novo Nordisk Insulin Aspart Injection, 3mL cartridges (300 units).

Colour availability varies by region. At this time, within Europe, the following colours are available:

  • Blue InPen™ compatible with Novo Nordisk insulin cartridges
  • Grey InPen™ compatible with Lilly insulin cartridges

The Guardian™ 4 system and InPen™ system apps have a wide range of compatibility with several Apple® and Android™ devices. You can find updated compatibility information https://www.medtronic-diabetes.com/en-gb/resources. here on our website. We recommend checking compatibility and switching off automatic operating system updates to ensure the best possible user experience.

InPen™ system is the first Smart* insulin pen that uses Bluetooth® technology and intelligence through an easy-to-use Smartphone app to help people administer correction and meal-time insulin doses.

*Smart insulin pen connects to a mobile app to provide dosing calculations, reminders and CGM system integration. Please refer to IFU.

As part of our Smart MDI system, a user can view CGM data from their Guardian™ 4 system by linking the app to their CareLink™ Personal account. At this time within Europe, only CGM data from Guardian™ 4 system can be viewed in the InPen™ system app.

Your Healthcare Professional or Medtronic representative may provide training on the Smart MDI system. Additional resources can be found at the Medtronic Diabetes Learning Hub.

Yes, multiple InPen™ Smart insulin pens can be synced with one app account.

Cartridges are not included with InPen™ system. Your Healthcare Professional will provide you with your prescription for your diabetes management supplies.

Medtronic are looking to provide comprehensive self-funding options for those living with diabetes. We anticipate we will be in a position to make self-funding options available in late spring 2022.

  1. Abraham SB, et al. Improved Real-World Glycemic Control With Continuous Glucose Monitoring System Predictive Alerts. Journal of Diabetes Science and Technology 2021; 15(1):91–97
  2. Smith M, et al, E5 , SIPs Improve Time Below Range in MDI Therapy, AMCP Congress 2020
  3. Adolfsson P, Væver Hartvig, Kaas A, Møller JB, Hellman J. Increased Time in Range and Fewer Missed Bolus Injections After Introduction of a Smart Connected Insulin Pen. Diabetes Technology & Therapeutics, 2020;22(7):online ahead of print
  4. Dicimbrini I et al, Effects of real‑time continuous glucose monitoring in type 1 diabetes : a meta‑analysis of randomized controlled trials, Acta Diabetologica 2020 doi: 10.1007/s00592-020-01589-3
*MDI = Multiple Daily Injections
If CGM readings do not match SG or expectations, use a blood glucose meter to make diabetes treatment decisions. Refer to System User Guide

Thanks to insulin dose reminders and bolus calculator
Time in Range is the percentage of time that people with type 1 diabetes spend in the optimal glycemic range of 70-180 mg/dL (3.9-10 mmol/L).
If CGM readings do not match symptoms or expectations, use a blood glucose meter to make diabetes treatment decisions. Refer to System User Guide.
Smart CGM predicts future high and low sensor glucose events up to 1 hour in advance and provides access to additional algorithms and insights that can inform users of clinically relevant glucose patterns. Please refer to IFU.
Smart insulin pen connects to a mobile app to provide dosing calculations, reminders and CGM system integration. Please refer to IFU.

Information contained herein is not medical advice and should not be used as an alternative to speaking with your doctor. Discuss indications, contraindications, warnings, precautions, potential adverse events and any further information with your health care professional.

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